Blar i forfatter "Esaiassen, Eirin"

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    • Antibiotic therapy in neonates and impact on gut microbiota and antibiotic resistance development: a systematic review 

      Fjalstad, Jon Widding; Esaiassen, Eirin; Juvet, Lene Kristine; van den Anker, John; Klingenberg, Claus Andreas (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-11-22)
      <p><i>Objectives - </i>To systematically review the impact of antibiotic therapy in the neonatal period on changes in the gut microbiota and/or antibiotic resistance development. <p><i>Methods - </i>Data sources were PubMed, Embase, Medline and the Cochrane Database, supplemented by manual searches of reference lists. Randomized controlled trials (RCTs) and observational studies were included if ...

    • Antibiotics and probiotics to neonates-Adverse effects, impact on gut microbiota and antibiotic resistome, and Bifidobacterium pathogenicity 

      Esaiassen, Eirin (Doctoral thesis; Doktorgradsavhandling, 2018-02-16)
      The main objective of this thesis was to systematically review potential side effects of antibiotic therapy in neonates and to study the gut microbiota composition of preterm infants receiving probiotic prophylaxis. This thesis includes two systemic reviews, a prospective longitudinal multi-centre trial investigating the gut microbiota in preterm infants receiving probiotics compared to preterm ...

    • Antimicrobial susceptibility and body site distribution of community isolates of coagulase-negative staphylococci 

      Cavanagh, Jorunn Pauline; Wolden, Runa; Heise, Philipp; Esaiassen, Eirin; Klingenberg, Claus; Aarag, Elizabeth (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-09-07)
      The primary aim of this study was to determine antimicrobial resistance in coagulase-negative staphylococci (CoNS) from healthy adults in the community. Healthy adults (n = 114) were swabbed on six body sites; both armpits, both knee pits and both sides of the groin. Species determination was performed using Matrix Assisted Laser Desorption Ionization – Time of Flight (MALDI-TOF) and susceptibility ...

    • Bronkiolitt skal ikke behandles med glukokortikoider eller antibiotika 

      Nordal, Ellen Berit; Granslo, Hildegunn Norbakken; Esaiassen, Eirin; Leknessund, Carina Benedikte Bjørkvoll; Forsdahl, Bård Anders (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-30)
      Vi er inne i en hektisk sesong med virale luftveisinfeksjoner. Respiratorisk syncytialvirus (RS-virus) er den hyppigste årsaken til bronkiolitt hos barn. Pediatriveilederen er tydelig på at perorale glukokortikoider ikke har noen plass i behandlingen av bronkiolitt og at det sjelden er behov for antibiotika.

    • Development of early life gut resistome and mobilome across gestational ages and microbiota-modifying treatments 

      Bargheet, Ahmed; Klingenberg, Claus Andreas; Esaiassen, Eirin; Hjerde, Erik; Cavanagh, Jorunn Pauline; Bengtsson-Palme, Johan; Pettersen, Veronika K. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-13)
      Background - Gestational age (GA) and associated level of gastrointestinal tract maturation are major factors driving the initial gut microbiota composition in preterm infants. Besides, compared to term infants, premature infants often receive antibiotics to treat infections and probiotics to restore optimal gut microbiota. How GA, antibiotics, and probiotics modulate the microbiota’s core ...

    • Effects of Probiotic Supplementation on the Gut Microbiota and Antibiotic Resistome Development in Preterm Infants 

      Esaiassen, Eirin; Hjerde, Erik; Cavanagh, Jorunn Pauline; Pedersen, Tanja; Andresen, Jannicke Hanne; Rettedal, Siren; Støen, Ragnhild; Nakstad, Britt; Willassen, Nils Peder; Klingenberg, Claus (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-11-16)
      <i>Objectives</i>: In 2014 probiotic supplementation (<i>Lactobacillus acidophilus and Bifidobacterium longum subspecies infantis;</i> Infloran®) was introduced as standard of care to prevent necrotizing enterocolitis (NEC) in extremely preterm infants in Norway. We aimed to evaluate the influence of probiotics and antibiotic therapy on the developing gut microbiota and antibiotic resistome in ...

    • The synthetic antimicrobial peptide LTX21 induces inflammatory responses in a human whole blood model and a murine peritoneum model 

      Granslo, Hildegunn Norbakken; Aarag, Elizabeth; Esaiassen, Eirin; Christophersen, Lars; Jensen, Peter Østrup; Mollnes, Tom Eirik; Moser, Claus; Flægstad, Trond; Klingenberg, Claus; Cavanagh, Jorunn Pauline (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-03-27)
      The global spread of antimicrobial resistance and the increasing number of immune‐compromised patients are major challenges in modern medicine. Targeting bacterial virulence or the human host immune system to increase host defence are important strategies in the search for novel antimicrobial drugs. We investigated the inflammatory response of the synthetic short antimicrobial peptide LTX21 in two ...

    • Utredning og diagnostikk av dyp venetrombose ved Universitetssykehuset i Nord-Norge. Klinisk evaluering og måling av CRP og D-dimer i vurdering av sannsynlighet for å utelukke DVT 

      Lægreid, Ingvild Jenssen; Esaiassen, Eirin (Master thesis; Mastergradsoppgave, 2006-09)